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KMID : 0356920150680040392
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Korean Journal of Anesthesiology
2015 Volume.68 No. 4 p.392 ~ p.396
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Time course of end-tidal desflurane concentration during delivery and elimination according to the type and location of filters in a semi-closed circuit system
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Park Sung-Wook
Chung Jun-Young
Moon Eun-Jin
Kang Young-Jin
Kang Jong-Man
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Abstract
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Background: The aim of this study was to determine whether the end-tidal concentration of desflurane would be affected by a breathing circuit system filter attached at two different positions in anesthetic breathing circuit systems.
Methods: An artificial lung was ventilated under five different conditions. The first group was without any filter or desflurane (n = 5, sham), the second was with desflurane but without any filter (n = 10, control), the third group had a bacterial filter on the expiratory limb (n = 10), and the fourth and fifth groups had a viral/bacterial filter added on the expiratory limb (n = 10) or at the Y-piece of the breathing circuit (n = 10), respectively. In all groups except the sham, administration of 10% desflurane was performed for 5 minutes and then stopped for 5 minutes.
Results: The mean (SD) end-tidal concentration of desflurane for the groups described above peaked at 0 (0), 9.8 (0.1), 9.8 (0.1), 8.5 (0.1), and 6.7% (0.1) (P < 0.001), respectively. There was no difference in the desflurane concentrations and the expired tidal volume over time between the control and bacterial group, but there was a significant difference between the control and the fourth and fifth groups (P < 0.001).
Conclusions: Filters can affect the expiratory desflurane concentration during anesthesia.
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KEYWORD
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Concentration, Desflurane, Filter, Tidal volume
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